Neoadjuvant chemotherapy with radical cystectomy in the treatment of muscle-invasive bladder cancer

The results of the combined treatment of 36 patients with muscle-invasive bladder cancer treated with neoadjuvant combination chemotherapy with Gemzar + Cisplatin. The control group included 167 patients who underwent surgical treatment. In multivariate statistical analysis found that the use neoadjuvant combination chemotherapy significantly improves long-term results of treatment at a moderate degree of tumor differentiation (G2), bladder cancer II stage, in the absence of lymph node involvement (N0) and in patients younger than 65 years.