Anorexia nervosa as a variation of the suicidal phenotype

As a result of the analysis of modern literature it has been shown that nervous anorexia (AN) is a multifactorial polyetiological mental disorder with a high tendency to commit hard suicides, the pathogenesis of which is associated with the presence of a group of polymorphic genes in the genome of patients. The specificity of accumulation in the genome of patients of patterns of single-nucleotide polymorphisms, occurring in different accumulation variants, determines the clinical phenotype of AN and the severity of this pathology. The onset of this pathology is probably associated with an increase in the concentration of estrogens in the pubertal and post-pubertal periods and, possibly, dietary intake of steroids of animal and/or plant origin with estrogenic activity, or other alimentary regulators of lipid nature. In addition, the studied data allowed us to conclude that AN is one of the forms of the suicidal phenotype.