Low-temperature Argon Plasma: from the Biophysical Foundations for practical application in clinical medicine

Автор: Zemlyanoi A.B., Evseev M.A., Markevich P.S., Filippov A.V., Dolgikh R.N., Tyukalov Yu.A., Nalbandian R.T., Zelenina T.A., Gromova A.A., Gerasimov N.G., Pesterev I.A., Koretsky D.S.

Журнал: Московский хирургический журнал @mossj

Рубрика: Экспериментальные исследования

Статья в выпуске: 3 (93), 2025 года.

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Introduction. Low-temperature argon plasma (LTAP) is increasingly being used in medicine due to its antimicrobial, anti-inflammatory, and regenerative properties. Objective. To compare the energy parameters of ultraviolet radiation emitted by the "Plazmoran" and "PLAZON" devices to evaluate their effectiveness in clinical practice. Materials and Methods. The study was conducted using two devices: – "Plazmoran" (operates on argon) – "PLAZON" (uses air). The energy illumination of UV radiation was measured at distances of 10, 15, and 20 cm. For "Plazmoran," mode B2 was used; for "PLAZON," the maximum mode was applied. Results. "Plazmoran" demonstrated 5 times higher illumination in the UV-C range compared to "PLAZON." This is attributed to the use of argon, which ensures stable recombinant radiation. With increasing distance, the effectiveness decreases due to the absorption of UV radiation by oxygen in the air. Clinical data confirm the efficacy of LTAP in treating wounds, burns, dermatological diseases, and blast injuries in children. The application of plasma promotes faster wound healing, reduces inflammation, and activates tissue regeneration. Conclusion. The "Plazmoran" device has higher energy characteristics and more stable effects, making it preferable for clinical use. The use of argon eliminates unwanted chemical reactions and enhances therapeutic efficacy. The obtained results confirm the promising prospects for further integration of LTAP technologies into medical practice.

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Low-temperature plasma, ultraviolet radiation, antimicrobial action, wound regeneration, clinical efficacy

Короткий адрес: https://sciup.org/142245645

IDR: 142245645   |   DOI: 10.17238/2072-3180-2025-3-178-189

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