About formation of nephrons in embryogenesis

Morphogenesis of nephrons passes in embryonal kidney similarly with morphogenesis of intestinal villuses and crypts, and pancreatic lobules and acinuses in embryogenesis too. Despite on organic features of construction and development of these structures, it is determined similar processes in mechanics of their development - formation and degeneration of pseudostratified epithelium or blastema in bud of organ, moreover epithelium plays leading role in the interactions with surrounding mesenchyme. Features of origin (from entoderma or from mesoderma) and prospects, purposefuiness of development of epithelium (the surface or the glandular) determine organic and local features of observing processes, but quite not exclude general traits of epithelium’s development in different organs. Study by cytology and cytochemistry, molecular biology of these not abolishes such law-governed nature of nephronogenesis, and only makes more precise its details on corresponding levels of organization of biosystem.