On the relationship between innate and adaptive immunity in psoriasis

There is an overview of the current literature data, which reflects the key aspects of the etiology and pathogenesis of psoriasis. A genetically determined, multifactorial nature of the dermatosis was displayed. There were summarized numerous domestic and foreign data on immunological (cellular, humoral, mediator, extravasation, angiogenesis) and non-immune mechanisms of genesis of psoriasis.