Evaluation of thrombocytes aggregation and lipid peroxidation in patients with ischemic heart disease with bypass surgery in history

The purpose of our study is to investigation of thrombocytes aggregation and lipid peroxidation in patients with ischemic heart disease with bypass surgery in history and without it. Were enrolled 128 patients: 82 patients with bypass surgery in period from 1 to 10 years; 46 patients with stable ischemic disease 2-3 functional class. All patients got statines, ACE inhibitors and beta-blockers. In group of patients with history of bypass surgery more then 5 years levels of spontaneous thrombocytes aggregation were the highest and levels of ADP induced thrombocytes aggregation were lower then in group of patients with bypass surgery history less then 5 years. In persons without bypass surgery in history were observed high levels of thrombocytes aggregation which can evidence of high thrombogenic potential in such patients.