Estimation of capacity of high resolution mass spectra for analysis of complex mixtures

Автор: Lutvinsky Ya. I., Makarov V.V., Kozlov B.N., Podolskaya E.P., Trufanov A.S., Apatskaya M.V., Krasnov I.A., Krasnov N.V., Verentchikov A.N.

Журнал: Научное приборостроение @nauchnoe-priborostroenie

Рубрика: Масс-спектрометрия для биотехнологии. Интерпретация данных, методология, применение

Статья в выпуске: 3 т.16, 2006 года.

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Using multireflecting time-of-flight mass spectrometers (MR TOF MS) with an improved resolution R, significant improvement in peak capacity and information content of mass spectra is demonstrated. A model digest of two protein mixtures was analyzed in two modes - infusion and LC-MS. Computer simulations show the advantage of MR TOF MS compared to conventional TOF MS for analysis of the whole bacteria digests using the method of AMT Tag.

Короткий адрес: https://sciup.org/14264443

IDR: 14264443

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