Assessment of cardiovascular risk factors in patients with chronic periodontitis

Aim: to estimate the cardiovascular risk in patients with chronic periodontitis (CP) different severity. Material and Methods. 2400 persons (65.6% male, aged from 40 to 64 years) were examined. Body mass index, lipid spectrum, blood glucose and C-reactive protein levels were determined, and tonometry was performed. The 10-year risk of a cardiovascular event was calculated using SCORE (Systematic Coronary Risk Evaluation) and Reynolds Risk Score. The concentration of interleukin-6 (IL-6) in the oral fluid was studied. Results. Patients with moderate to severe CP are characterized a high incidence of the main cardiovascular risk factors (arterial hypertension, smoking, dyslipidemia, obesity) compared to those with person with intact periodontal tissue and patients with mild CP For patients with CP with a moderate risk of fatal cardiovascular events on the SCORE, it is advisable to calculate the cardiovascular risk on the Reynolds Risk Score too. The oral fluid's level of IL-6 in the patients with CP may be considered as an additional marker of high risk of fatal cardiovascular events. Conclusion. The relation between the results of severe CP as missing teeth, loss of periodontal bone and the risk of fatal cardiovascular events is important for clinical use and may be used as an additional cardiovascular risk marker for patients with chronic periodontitis.