Assessment of cases of secondary immunodeficiency in patients with acute leukemia

Early diagnosis of oncohematological diseases in children is extremely difficult due to the non-specificity of the primary symptoms, which are often hidden under the "masks" of other diseases. Oncological alertness and knowledge of the likely symptoms will allow the practitioner to diagnose this pathology earlier and, consequently, significantly improve the prognosis for the patient. Despite the progress of laboratory diagnostics, it is difficult to detect leukemia in children at early stages, because for the appearance of characteristic changes in the hemogram, the tumor must reach a critical mass, and the manifestation of ALL is associated with blast infiltration of various organs with a violation of their function. Clinical symptoms in this case are ahead of laboratory changes, and the child is not hospitalized in a specialized hematology hospital.