Evaluation of the therapeutic efficacy of the biologically active composition of microbial origin “Symbion-D in dyspepsia in calves

The current range of medicines with antibacterial activity, enzyme preparations and probiotics, when used in mono mode, are often ineffective, and their combination leads to an increase in the cost of the course of treatment and an increase in the cost of the final product. In this regard, a search is underway for new drugs that combine the effects of all of the above groups of drugs. The paper presents an assessment of the therapeutic efficacy of an experimental sample of a biologically active composition of microbial origin (BACMO) Symbion-D based on acetic acid bacteria, yeast and natural polysaccharide. The data of clinical and hematological studies before and after treatment of dyspepsia in calves are presented. The studies were carried out in 2019 on 60 calves of the neonatal period of the Holstein breed belonging to the Federal State Unitary Enterprise “Omskoyeˮ. The calves of the experimental group were injected with BACMO Symbion-D at a dose of 20-30 ml per head and fed daily individually for 5-7 days, depending on the weight of the calf and the severity of the disease. Clinical recovery of 36% of calves starting from the second day, and 80% of heads by 7 days from the start of treatment has been established. Recorded changes in blood parameters indicate the normalization of hemoglobin formation and protective functions of the body 7 days after the start of Symbion-D treatment. The biochemical status of calves against the background of the use of Symbion-D reflects the intensity of protein metabolism processes due to the stimulation of the synthetic function of the liver.