Risk factors for venous thromboembolism in glioma patients

Background: Ranking third in the cause of death structure, venous thromboembolism (VTE) is a frequent complication in patients with central nervous system tumors. Objective: To assess the incidence of venous thrombosis and its risk factors in glioma patients based on retrospective data. Methods: Our retrospective study included 186 glioma patients from the Neurosurgery Department of Almazov National Medical Research Centre. Results: The VTE incidence was 8% in patients with brain neoplasms. Comparative analysis of 2 groups to identify VTE predictors showed that the probability of thrombosis increases with factors leading to the patient immobilization: altered mental status (40% [n = 6] in the VTE group vs 18% [n = 30] in the non-VTE group, OR: 3.1 [95% G: 0.8-10.6], P = .080), neurological deficit (67% [n = 50] vs 29% [n = 10], OR: 4.8 [95% G: 1.4-18.7], P = .007), and bed rest for more than 3 days (33% vs 4%, OR: 13.1 [95% G: 2.7-62.8], P