Isolation of microsomes from rat liver: an optimization protocol
Автор: Morkovin E.I., Dotsenko A.M., Strygin A.V., Tarasov A.S.
Журнал: Волгоградский научно-медицинский журнал @bulletin-volgmed
Рубрика: Новые методы в эксперименте и клинике
Статья в выпуске: 1 (53), 2017 года.
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The current study was undertaken to optimize the experimental protocol of the rat liver microsome isolation. To verify the feasibility of the method, we evaluated respiratory chain activity of microsomes using a fluorometric method. We conclude that the optimized protocol can be used at the initial stage of in vitro drug metabolism studies.
Метаболизм лекарств in vitro, microsome, hepatocytes, microsomal oxidation, drug metabolism in vitro, perfusion
Короткий адрес: https://sciup.org/142149212
IDR: 142149212
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