Features of circadian rhythm of blood pressure in patients with chronic heart failure associated with chronic kidney disease

Despite the frequent combination of CHF and chronic kidney disease (CKD), main features of circadian rhythm in such patients are still poorly understood. The study included 180 patients with CHF. 86 patients had glomerular filtration rate (GFR) above 60 ml/min/1,73 m 2, 57 patients – moderate decrease (GFR from 45 to 59 ml/min/1,73 m 2), 37 patients – severe decrease (below 45 ml/min/1,73 m 2). Correlation of SBP and DBP ND with GFR was revealed. Multivariate regression analysis confirmed an independent relationship between reduced GFR below 45 ml/min/1,73 m 2 and SBP and DBP ND. The study showed significant circadian rhythm disorders in patients with CHF associated with CKD.