Patterns of gene polymorphism and immune status in children exposed to benz(a)pyrene
Автор: Dolgikh O.V., Krivtsov A.V., Bubnova O.A., Gorshkova K.G., Dianova D.G., Vdovina N.A., Pirogova E.A., Bezdenezhnykh V.A.
Журнал: Вестник Пермского университета. Серия: Биология @vestnik-psu-bio
Рубрика: Медико-биологические науки
Статья в выпуске: 4, 2014 года.
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The features of sulfotransferase's 1 (SULT1) gene frequencies distribution, cytochrome (CYP1A1), tumor necrosis factor (TNFa) and endothelial NO-synthase (NOS3) in children under exposure to benz(a)pyrene have been analyzed. The higher prevalence of frequencies of heterozygote variants, minor alleles of sulfotransferase genes, tumor necrosis factor and endothelial NO-synthase, as well as their association with contamination of the biological media with chemical mutagens and specific immunological response to the hapten have been detected.
Sulfotransferase gene, gene polymorphism, benz(a)pyrene
Короткий адрес: https://sciup.org/147204702
IDR: 147204702
