Features of the immune status of pupils under the influence of heterogeneous physical factors of a non-ionizing nature

A hygienic assessment of a number of physical factors of the school environment was carried out and the features of the immune status of students under the influence of these factors in the gymnasium of Perm (observation group) were described in comparison with the features of the same indicators in students of a school in one of the cities of the Perm Region. All the studied physical factors, with the exception of the aeroionic composition of the air, did not exceed the maximum permissible levels established by sanitary requirements. In the air of all the examined classrooms of the gymnasium, the number of negative and positive aeroions was found to be inconsistent with the norm; at school, in a number of classrooms, the aeroion composition of the air corresponded to the norm. A comparative analysis of the immune system indicators revealed the presence of age-dependent changes in the expression of CD-receptors of lymphocytes in the presence of additional sources of physical factors. In the students of the observation groups in primary, primary and high school, changes in individual classes of immunoglobulins were found both in relation to the comparison groups and in relation to the physiological norm. An imbalance of pro- and anti- inflammatory cytokines was found in children in primary and secondary schools of the gymnasium.