Title features of the modeling of the stump in animals for the installation of osteointegrated implants

Introduction. The formation of a stump, followed by implantation of osteointegrated implants, is a serious problem. During preclinical tests, various animal models are used. We studied the features of the modeling of the stump and postoperative conducting on rabbits. The aim of the study is to determine the features of modeling the stults of experimental animals and postoperative management for the subsequent installation of osteointegrated implants. Materials and methods. The study included 14 rabbits of the Soviet chinchilla breed. Transtibial amputation of the hind limb was performed with the formation of the anterior and predominant size of the posterior fasciocutaneous and muscle flaps; osteotomy was performed with an oscillating saw with saline cooling. The self-tapping sleeve was inserted into the medullary canal by screw movements to the level of the saw; the wound was closed in layers without drainage. We have developed and applied an individual 3D-modeled immobilizing sleeve mounted on top of an aseptic bandage. Results. A detailed protocol of operation and the stages of postoperative conducting animals for the subsequent installation of osteointegrated implants have been developed. A new immobilizing rear limb of the sleeve rabbit using 3D modeling and additive technologies is proposed. The advantages and disadvantages of the proposed methodology were identified. Conclusion. A new approach to modeling of skin-muscle flaps allows minimizing tissue injuries in the postoperative period and reducing the frequency of necrosis. The manufacture of an immobilizing sleeve protects the stump from mechanical damage. The experience of forming a stump, the manufacture of implants and immobilizing devices, as well as postoperative management, can be used in preclinical studies to test new materials and structures, as well as for experiments on a large animal model.