Human pathophysiology in the conditions of north Russia

The article examines the adaptive mechanisms and features of the development of pathology in the inhabitants of the North. It has been determined that in more than 70% of the newcomer population in the North, adaptation mechanisms cannot ensure long-term preservation of health. Chronic stress turns into pathological conditions. It is noted that the stress reaction is triggered by the activation of neurohormonal mechanisms, followed by an increase in the function of the immune system, the induction of enzymes, the activation of metabolic processes, and an increase in the efficiency of the functioning of other homeostatic systems of the body.