Pathomorphology, clinic and treatment of changes in the cardiovascular system in COVID-19

The article presents a review of the scientific literature containing data on the pathogenesis, diagnosis and treatment of cardiovascular consequences of a new coronavirus infection. Heart damage is observed in 7-28% of hospitalized patients with COVID-19. Myocardial damage when exposed to coronavirus infection can be realized through two pathological mechanisms: direct damage to the myocardium due to the interaction of SARS-CoV-2 with myocardial receptors of angiotensin converting enzyme 2, as well as indirect damage to the myocardium, which can be caused by cytokines and other pro-inflammatory factors, microcirculation disorders, hypoxic changes in cardiomyocytes.