Placenta-like alkaline phosphatase as cows’ postpartum diseases predictive marker

The aim of research is to study the level of enzymatic activity of total and placental alkaline phosphatases in the interlactation period and the possibility of using these indicators as prognostic markers of postpartum sequela in cows. Research objectives are to study the dynamics of changes in the cows’ blood within the interlactation period, the level of enzymatic activity of total alkaline and placental alkaline phosphatases (PAP); to determine the prognostic information value of placental alkaline phosphatase in the prognosis of postpartum diseases in cows. the experiment was carried out in FSBSI FASCA Breeding Plant "Komsomolskoye", Pavlovsky District, the Altai Region. Two groups were formed from cows: a control group in the amount of 61 animals with the physiological course of childbirth and the postpartum period and an experimental group in the amount of 43 animals with postpartum sequela, which included endometritis after spontaneous separation of the placenta; retention of the placenta; postpartum paresis. For laboratory studies, blood was taken from cows from the tail vein in the morning before feeding, once 45–15 days before calving. Significant changes in the enzymatic activity of PAP in comparison with animals of the control group, both 45 and 15 days before calving, were noted only in animals with retention of mem-branes by 45 and 16.7 U / L, respectively (p < 0.05). A significant decrease in the blood of pregnant cows 15 days before calving, the level of the enzymatic activity of the PAP below 14.0 U / L can serve as a prognostic sign of the development of postpartum sequela, in particular, in particular placenta (amniotic membranes) retention.