Polyfunctional multitarget drugs as a basis of pharmacology of the 21st century
Автор: Vasilyev Pavel M., Kosolapov Vadim A., Spasov Aleksandr A., Yanalieva Laura R.
Журнал: Природные системы и ресурсы @ns-jvolsu
Статья в выпуске: 1 т.8, 2018 года.
Бесплатный доступ
Due to the fact that all diseases began to be considered as multifactorial, the main direction of pharmacology in the 21st century is the design of multitarget ligands. The relevance of this approach is confirmed by the authors’ research in the field of analysis of the spectrum of affinity for nine ion channels of the heart for three antiarrhythmic drugs, as well as the results of initiatory research into the search for fundamentally new multifunctional multitarget inhibitors of glycation end-product receptors.
Network pharmacology, drugs, multi-target ligands
Короткий адрес: https://sciup.org/149129616
IDR: 149129616 | DOI: 10.15688/jvolsu11.2018.1.6