Portable mass spectrometer with membrane sample input for analysis of percutaneous CO2 emission

A portable mass spectrometer with a membrane method of sample input developed earlier showed stable reproducibility and speed of analysis. To reduce the analysis time, the impact on the blood flow in the work and for ease of use an upgraded membrane interface has been developed. The reduction of the analysis time was achieved by the use of a new membrane interface design, thinner membrane and modified PTFE tube. A mass spectrometer with a membrane interface was calibrated. The results of the development and testing of a non-invasive mass spectrometric method for measuring the transcutaneous CO2 release of healthy people at 3 points of the body are presented. The concentration of CO2 released through the skin was measured during moderate and severe physical exertion. The reproducibility of the results of the method application is shown.