A proposal for a new strategy, on the base of the optimization of conventional radiotherapy - tumor sensitization by sanazole with normal tissue protection by vitamin glycosides

In conventional radiotherapy, a protocol of 2 Gy irradiation, 5 times a week, for 6 weeks (60 Gy) in total has being performed for cancer patient. Radiosensitizers have been developed in order to enhance the efficacy of radiation in the conventional radiotherapy. On the other hand, for the purpose to avoid immediate side effect of radiotherapy such as nausea, vomiting, suffer from diarrhea, radiotherapy has been obliged to limit total dose of irradiation, and to perform fractionated radiation treatment. We propose a new strategy of conventional radiotherapy, tumor sensitization by Sanazole (AK-2123) with normal tissue protection by Vitamin Glycosides.