Using the buccal graft (buccal mucosa) for arterioplasty of great vessels

Aim. The aim of this study was to develop and substantiate the possibility of using a buccal graft for arterioplasty of great vessels.Material and Methods. The experiments were carried out using 48 animals including 45 mongrel rabbits weighing 5-7 kg and three dwarf pigs of the minipig breed weighing 35-45 kg. Vascular wall injury was modeled from the median laparotomy in all animals on the example of infrarenal abdominal aorta followed by plastic surgery of the vessel with a buccal graft. The animals were removed from the experiment in time-frame of up to 270 days.Results. No stenoses, deformities, or aneurysmal extensions of the abdominal aorta were detected according to data of instrumental studies. The morphodynamic processes occurring in the buccal graft were characterized by the changes in the internal lining of autograft in the form of restructuring and acquisition of morphological traits of endothelial lining of the vessel and disappearance of the features intrinsic to the non-keratinized stratified squamous epithelium present in oral cavity.Conclusions. The use of buccal graft as a material for arterioplasty of the great arteries demonstrated high efficiency in the follow-up period of up to 270 days. The use of this autograft was not associated with the development of arterial pseudoaneurysms in the arterioplasty area.