Use of immunostimulators in the prevention of coronavirus disease in calves

Vaccination and passive immunization, disinfection and biosecurity, feeding and feeding, care, hygiene and immune status of animals are essential to prevent BCoV diseases, limit the use of antibacterial drugs and reduce the subsequent emergence of microbial resistance, improve the quality of animal products and animals. Multivalent vaccines are now available to limit the spread of the virus and achieve hyperimmune herd passive immunization in calves, which may protect or reduce the severity of BCoV diarrhea in calves. The importance of passive immunization is noted. An oral live vaccine has also been developed to prevent diarrhea in calves. Studies have also been conducted on the use of intranasal BCoV vaccination in calves against bovine respiratory disease and winter dysentery.