Application of mass-spectrometry for control of antibiotics in milk

Using the example of lincomycin, the possibility of using quantitative mass spectrometry for the detection of antibiotics in a wide range of concentrations in the milk of treated animals was demonstrated. A calibration curve was constructed to determine the concentration of lincomycin in milk for MX5310, a time-of-flight mass spectrometer with a source of ions of the "electrospray" type and an orthogonal ion delivery method. Lincomycin was found in milk, at its concentrations of smaller and larger then maximum allowable concentration.