Proatherogenic lipid and lipoprotein metabolic disturbances in patients with rheumatoid arthritis

Abnormalities in the blood cholesterol transport system play a leading role in the development of atherosclerotic vascular lesions in rheumatoid arthritis (RA). The article analyzes the lipid profile in patients with untreated RA. It gives data on the impact of inflammation on proatherogenic lipid and lipoprotein metabolic disturbances and defines the need to explore high-density lipoprotein subfractions and their functions, namely, reverse cholesterol transport in patients with RA as a more promising method for assessing cardiovascular risk.