Distribution of blood groups antigensin moksha and erzya (Republic of Mordovia)

A genogeographical map of the Russian Federation is necessary for scientifically based safe provision of phenotype-matched blood. Assessment of frequency distribution of transfusion-dangerous red blood cell antigens in different geographical regions of the Russian Federation, as well as among representatives of different nationalities and ethnic groups will become a basis for problem-solving in ethnography, ethnog-eny, sociology and other fields of science and culture. The aim of the study was to analyze the distribution of blood-group antigens in the erythrocyte phenotype in ABO and Rh blood groups, as well as Kell, Ow, M, and N antigens in the indigenous population of the Republic of Mordovia (ethnic groups the Erzya and Moksha). Materials and Methods. The survey was conducted in Krasnoslobodsky, Torbeevsky, Kovylkinsky, Insara (Mokshan territory), Bolsheignatovsky, Ardatov, Dubensky (Erzyan territory), and Tengushevsky (this is the region with an ethnic subgroup Erzya, who speak Shokshin dialect of the Erzyan language) regions of the Republic of Mordovia. The authors examined 681 people, including 294 Moksha and 387 Erzya. Prevalence and frequency rate of blood-group antigens of ABO, Rh, as well as Kell, Cw, M and N antigens were studied. Typing for erythrocyte antigens was carried out by a hemagglutination reaction with monoclonal antibodies. Results. The most common blood groups for the Moksha and Erzya are O(I) (34.01 %), followed by A(II) (32.99 %) and A(II) (36.69 %), followed by O(I) (31.26 %) correspondingly. Rh+ factor among the Moksha occurs in 84.69 %, and among the Erzya in 83.97 %; Rh- occurs in 15.3 % and in 16.18 % respectively. The incidence of Kell antigens in the Moksha is 7.14 % (all positive samples are represented by Kk phenotype); in the Erzya the incidence is 7.4 % (among them 28 samples are with Kk phenotype (7.2 %) and 1 sample KK phenotype (0.25 %)). The incidence of Cw antigen in the Moksha is 1.7 %; in the Erzya it is significantly higher, namely 5.68 %. Significant differences in the prevalence of M and N antigens among the examined ethnic groups were noted.