Distribution of bioelements in certain organs and tissues of normal and diabetic Wistar rats

A study of wide spectrum of micro- and macroelements in certain organs and tissues of normal and alloxan-induced diabetic (DM) rats has been performed. It is shown that regardless of the type of tissue, ion content was distributed as follows in descending order: K > Na > Mg > Ca > Fe > Zn > Cu > Mn > Mb ≥ Cr. However, for each element some differences in its distribution among organs were observed. In DM rats significant increase of ion concentration has been found: Cu, Fe and Zn - in the kidney; Fe - in the liver; Ca, K, Mg, and Fe - in the pancreas; Fe - in liver and muscle tissue. Intake of a Curcuma rhizome powder by healthy rats practically did not lead to change of the maintenance of elements in tissues, but in DM rats it caused significant increase of Mg and Zn content only in a kidney. Thus, Curcuma longa practically does not render influence on distribution of bioelements in organs and tissues of rats both in norm, and at DM. Possibly, the bioelements which are included in a plant, do not play an essential role in hypoglycemic effect of a phytopreparation described by us earlier.