Different changes of the serum albumin cobalt-binding capacity induced by various oxidants
Автор: Zaitsev Valery Gennadyevich, Litus Ekaterina Andreevna, Zhdanova Anna Vitalyevna
Журнал: Природные системы и ресурсы @ns-jvolsu
Рубрика: Биология и биотехнология
Статья в выпуске: 2 (2), 2011 года.
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Impact of in vitro oxidative modification of the bovine serum albumin (BSA) on its cobaltbinding capacity (CoBC) was studied. We found various oxidants differently changed CoBC of BSA. The Fenton's reagents producing hydroxyl radical decreased or not alter CoBC of BSA depending on composition of ones. In contrast, treatment of BSA by hypochlorous acid, a physiological oxidant, elevated CoBC of this protein. Probable causes of different effects produced by various oxidants is discussed.
Serum albumin, proteins, oxidative modification, fenton's reagent, hydroxyl radical, hypochlorous acid, cobalt
Короткий адрес: https://sciup.org/14967337
IDR: 14967337
