Tissue regeneration and oncogenesis - similarities and differences

Автор: Tkachuk Vsevolod A.

Журнал: Сибирский онкологический журнал @siboncoj

Рубрика: Лекция

Статья в выпуске: 2 т.20, 2021 года.

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Regenerative medicine represents the field of medicine that aims to grow lost or damaged human organs and tissues. The promise of regenerative medicine focuses on the development of therapy that can regenerate and restore tissues and organs in the human body. The regenerative medicine has the potential of cell renewal in our body, reaching about a kilogram per day, tens of tons in our life. Recent data indicate that a tumor is a tissue that largely repeats the pattern of growth and regeneration of normal tissue. Similar to normal stem cells, tumor stem cells are capable of initiating tumor and its growth. Scientists consider that cancer is a payment for multicellularity [1]. Undoubtedly, this potential must be learned to manage. This is a very difficult problem, since many fundamental mechanisms of cell formation and death have not been fully understood. The development of regenerative medicine as a fundamentally new type of medicine will make it possible not only to control stem cell renewal, but also to prevent malignant transformation. The identification of proteins, micro-RNAs and other factors that regulate the formation and death of cells will identify potential targets for both stimulating endogenous regeneration and controlling cancer.

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Regenerative medicine, oncogenesis, reprogramming, transdifferentiation, stem cells secretome

Короткий адрес: https://sciup.org/140254429

IDR: 140254429   |   DOI: 10.21294/1814-4861-2021-20-2-5-12

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