C34T-polymorphism of the AMPD1 gene associated with successful performance in wrestling

The article is devoted to the study of the molecular genetic determinants of a competitive success in wrestling on the example of the athletes from three ethnic groups. The aim of the present paper was to study genetic selection in the polymorphic system of the AMPD1 gene (rs17602729) and its influence on sports achievement and competitive success in wrestling. 781 individuals between 18 and 30 years of age participated in the research. The surveyed participants belonged to one of three ethnic groups: Russian sample: 92 non-athletes, 226- wrestlers; Altaian sample: 167 non-athletes, 96 - wrestlers; the Mongolians: 55 non-athletes, 145- wrestlers. In the function of the source of DNA were oral mucosa samples. The DNA isolation and genotyping have been made in LLC Lytekh laboratory, Moscow. There were significant differences of genotype distribution between three studied ethnic groups (Russians, Altaians and Mongols). The T-allelehas never been found among wrestlers and the control group from Mongolia...