Conjugation of lymphogenous metastatic spread and histologic pattern of infiltrative component of ductal breast cancer

The morphologic pattern of infiltrative ductal breast cancer (IDBC) in 383 patients aged between 28 and 80 years has been studied. The incidence of lymphogenous metastatic spread has been shown to be increased linearly as microalveolar structures are increased in infiltrative component of IDBC (from 75%). The detected relationship depends neither on patients' age nor neoadjuvant chemotherapy and the presence or absence of other structures of infiltrative component in the tumor. The pronounced evidence of microalveolar structures in the infiltrative component is a prognostic factor indicating a high probability of lymphogenous metastases in breast cancer patients.