The hemodynamics and renal function before and after pulmonary thromboendarterectomy

Objective: to study the pulmonary hemodynamics and kidney function in patients with chronic thromboembolic pulmonary hypertension (CTEPH) after pulmonary thromboendarterectomy (PTE). To analyze the main results of PTE. Material and methods: among 51 patients with CTEPH undergoing PTE, the group with chronic kidney disease (CKD) was identified. The main parameters of hemodynamics, such as cardiac output (CO), cardiac index (d), pulmonary arterial pressure (PAP), pulmonary vascular resistance (PVR), were determined. The cases of acute kidney injury (AKI) after PTE were identified. The correlation between hemodynamics and renal function was analyzed. Results: there was decrease of mean PAP, PVR and increase of CO and CI after PTE. In cases of AKI 1-2, the complete recovery of renal function were observed. Glomerular filtration rate (GFR) increased before discharge in patients with CKD and in other patients. Conclusion: the positive dynamics of renal function in patients with CTEPH after PTE is more probably associated with an increase in the С and renal perfusion.