State of immunoreactivity of patients with cervical cancer against the background of extracorporeal immunopharmacotherapy

The aim of the study was to study the state of cellular and humoral factors ofimmunity of cervical cancer patients on the background of using extracorporeal immunopharmacotherapy. The analysis showed that patients with cervical cancer was found aT-cell immunodeficiency, which was associated with CD4 + T-helper / inducer deficiencyagainst the background of an increase in CD8 + T-lymphocytes and increased activation oflymphocytes with the predominance of apoptosis of immunocompetent cells. After carryingout extracorporal immunopharmacotherapy with thymalin, activation of the T-cell link of immunity is observed. The revealed imbalance of the humoral link of immunity before and afterh / t and radiotherapy was associated with an imbalance of the main serum immunoglobulinsand an elevated CIC level of small and large values. Against the background of the use ofEIPHT with thymalin, normalization of humoral factors of immunity and activation markersof lymphocytes is observed. Thus, the method of extracorporal immunopharmacotherapy inour case turned out to be promising in the treatment of cervical cancer due to the possibilityof removing the effects of cancer and chemoradiation intoxication, as well as activating itsown system of antitumor protection of the organism.