Modern conceptions and manifestation features of self-harming behavior

To date several biological risk factors have been identified as contributing to suicidal and self-harming behavior. The differences relate to changes in key neurotransmitter systems (serotonergic, polyamine stress response, glutamatergic and GABAergic systems), inflammatory response, astroglial dysfunction, neuronal plasticity factor, which confirms the need to differentiate people who do have a suicidal motive and who are prone to non-suicidal self-injurious behavior out of the total number of suicidal attempts. Non-suicidal self-injury (NSSI) is defined as repetitive, deliberate, direct injury to the body without suicidal intent that is not socially acceptable. The NSSI Integrated Theoretical Model for Development and Support suggests that this type of behavior functions as a method of regulating emotional experience and social interaction when a stressful event occurs. The NSSI is currently included in section 3 of the DSM-5 and is classified as a recommended condition for further study. In the American Diagnostic and Statistical Manual of Mental Disorders, Revision 4 (DSM-IV-TR) and ICD-10, NSSI is coded as a symptom of borderline personality disorder.