Current approaches to the treatment of advanced ovarian cancer using PET / CT-guided hyperthermic chemoperfusion. A clinical experience

Background. Ovarian malignancies constitute the 8th most common cancer in women with regard to morbidity and the 6th most common with regard to mortality. Survival of patients with ovarian cancer depends on the type of surgery and the size of the residual tumour. An «aggressive» surgical approach is currently adopted in the treatment of ovarian malignancies, which is aimed at removing all visible tumour lesions and subsequent regional chemotherapy. However, outcomes of treatment remain unsatisfactory, which indicates a need for a search for new, alternative treatment methods. Intraperitoneal hyperthermic chemoperfusion is one of such methods being introduced into clinical practice. Purpose. To evaluate the effectiveness of hyperthermic chemoperfusion in complex therapy regimens for patients with advanced ovarian cancer after optimal interval surgery. Materials and methods. A retrospective, single-centre, non-randomized study was conducted at the State Budgetary Institution of Health Care Chelyabinsk Regional Clinical Centre of Oncology and Nuclear Medicine from January 2014 to February 2019...