Current approaches to conservative and combined treatment for locally advanced laryngeal cancer

The comparative analysis of results of conservative and combined treatment was carried out. The study group consisted of 400 patients with stage T 3–4M 0 laryngeal cancer who received concurrent chemotherapy and radiation therapy in combination with various physical N0–3radiomodifyers. The control group comprised 920 patients treated with the same technique but without systemic polychemotherapy. The 5-year relapse-free and overall survival rates were significantly higher in the study group than in the control group (concervative treatment: 71 % and 86 % versus 37 % and 64.8 %, respectively, р