Spectroscopy of peptides, proteins and oligonukleotides from solutions by ion mobility
Автор: Arseniev A.N., Alekseev D.N., Belchenko G.V., Gavrik M.A., Krasnov Nikolay Vasilevich, Koryakin P.S., Krasnov I.A., Kurnin I.V., Myaldzin Sh. U., Muradymov M.Z., Monakov A.G., Pavlov V.G., Zvereva A.V., Nikitina S.N., Podolskaya E.P., Prisyach S.S., Semenov S. Yu., Krasnov M.N., Samokish A.V.
Журнал: Научное приборостроение @nauchnoe-priborostroenie
Рубрика: Приборостроение для биофизики и биохимиии
Статья в выпуске: 1 т.25, 2015 года.
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The capability of producing an ion mobility spectra of peptides, proteins and oligonucleotides in positive and negative modes using an ion source with field desorption ion from solution under dynamic flow dividing spraying liquid at atmospheric pressure and normal conditions. As of the objects used solutions: aliphatic quaternary amines Me 4N and Et 4N, arginine (175 Da), reserpine (608.68 Da) in positive mode, macro biomolecules Human serum albumin (69 367 Da), Hemoglobin Human (16 000 Da), Apoferritin (445 000 Da), Myoglobin (17 083 Da), Chymotrypsinogen A (25 666 Da), and synthetic oligonucleotides doditsela sodium sulfate (265 Da) in positive and negative modes. The studies were conducted on the prototype analytical complex ES-IDS (electrospray ion source---ion drift spectrometer), developed at the request of FMBA of Russia under the Federal Target Program "National System of chemical and biological safety of the Russian Federation (2009-2014)".
Ion mobility spectrometer, peptides, proteins, oligonukleotides, electrospray liquid
Короткий адрес: https://sciup.org/14264961
IDR: 14264961
