Comparative evaluation of EUS-guided fine needle aspiration at pancreatic diseases

Background: Most often pancreatic cancer is diagnosed at later stages, the average detection rate at stages III and IV in Russia is 59.5% [1]. The “gold” stan- dard for the verification of pathological processes is histological examination, but, in connection with the localization of the pancreas, obtaining tissue with the least amount of complications is difficult.Methods: It was evaluated the results of eUS - guided fine needle aspiration at pancreatic diseases with examination on the material of 124 clinical observa- tions.Results: When comparing the three different diameter needle for eUS - guided fine needle aspiration with the “gold” standard: with a histological examina- tion based on the results of surgical intervention, or with the data of a catamnesis, the accuracy of setting the correct diagnosis in the group of fine needle aspiration biopsy with 19G needle (group 1) was within the confidence interval from 80.31% to 98.41 %, in group 2 - from 92.29% to 100%, in group 3 - 100%. In 46 cases (36.5%) revealed malignant neoplasms of the pancreas, 22 persons (17.5%) with pseudocysts of the pancreas, and 18 (14.3%) patients with inflammatory pseudotumor of the pancreas.Conclusions: eUS - guided fine-needle aspiration biopsy of the pancreas with different diameter needle allow verifying the pathological process of the pancreas.