Structural and morphometric parameters of the epidermis and the dermis at the seborrheic dermatitis and the seborrheic alopecia

The article presents the results of a comparative study of pathomorphological changes in the epidermis and dermis in seborrheic alopecia and seborrheic dermatitis. 26 patients aged 17 to 60 years with seborrheic dermatitis of the scalp (9 people) and seborrheic alopecia (17 people) were examined. As a control group, 9 healthy people were examined. Biopsy was performed in the lesion in the frontal-parietal area by means of a punch-scalpel No. 5 after infiltration anesthesia with 2% lidocaine in compliance with the rules of asepsis and antiseptics. Subsequently, the drug was fixed in 10% formalin and after standard histological wiring, the obtained sections with a thickness of 5 µm were stained with hematoxylin-eosin. Morphometric study of the epidermis was performed by means of an eyepiece micrometer. In the epidermis the thickness of the epidermis and its layers were determined: basal, spiny, granular. The following parameters were evaluated in the dermis: the presence of lympho-histiocytic infiltrates in the papillary and net dermis, mucoid swelling, sclerosis of the papillary dermis, as well as signs of destruction of the hair follicles...