The relations of economically valuable characteristics of the Saanen goats with different polymorphic variants of the IGF-I gene

The aim of the research was to study the SNPsg.5752G> C and A224G polymorphism of the IGF-I gene of Saanen goats and to analyze the associations of their genotypes with the level of milk production, reproductive qualities, and dynamics of live weight. The research problems were to carry out genotyping of animals on SNPs g.5752G> C and A224G of the gene of IGF-I PCR-PDRF by the method; to determine the frequency of the occurrence of allelic options and genotypes in analyzed selection of animals; to study the relationship of significant associations of allelic options with economically valuable signs of the goats. The research was conducted on the basis of JSC PZ ‘Prinevskoe’ (Leningrad Region). For the research 47 Saanen breed goats born in January, 2018 were selected. The determination of polymorphism of the gene of IGF-1 was carried out by PCR-PDRF method. For the identification of the connection of polymorphicoptions of the gene of IGF-I with useful and economic signs data on dairy efficiency of goats in the first lactation were collected (the yield of milk in 100 and 200 days of lactation, the coefficient of stability of lactation, the percentage of fat and protein in milk). Reproduction indicators are represented by the age of the 1st lambing, the number of kids in the litter, the insemination index in the second breeding season (breeding season), the duration of the service period and the interval between the first and second lambing. In the studied population of the goats, high frequency of the BB genotype (0.872) and the B allele (0.936) according to SNP g.5752G> C was noted. According to SNP A224G of the IGF-I gene, all the animals were the carriers of the GG genotype. Therefore, the search for the associations was performed only for SNP g.5752G> C of the IGF-I gene. The goats with the BB genotype were distinguished by high milk yield (P function show_eabstract() { $('#eabstract1').hide(); $('#eabstract2').show(); $('#eabstract_expand').hide(); }