Tartrat-resistant asid phosphatase is the biochemical criterion of metastases in bones

Determination of tettat-resistant acid phosphatase 5b (TRAP 5b) level was shown can be used as a marker of metastatic involvement in bones. Diagnostic sensitivity and specificity rates were 82% and 87%, respectively for patients with breast cancer and 71% and 83,4for patients with prostate cancer. The determination of this marker in cancer patients, especially in breast cancer patients, can promote the increase in the accuracy of early detection of bone metastases, the assessment of metastatic involvement in bones and the treatment efficiency monitoring.