Hygienic and toxicological safety assessment of nano-dispersed silicon oxide

The findings of the experimental study performed within the preliminary hygienic and toxicological assessment of nano-dispersed silicon oxide, which was endogastrics administered to white nonlinear mice once, showed that, under acute oral exposure to silicon oxide, nanodispersed particles were 2-fold more toxic and cumulative (category 3, according to the oral LD50 values) than dispersed solution with micro-sized particles (category 4).