Participating of chemical elements in connective tissue dysplasia at the aortic aneurysm

The elemental content (S, Cl, K, Ca, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, As, Se, Br, Rb, Sr) was investigated by X-ray fluorescence elemental analysis in the aortic wall of 50 patients with IHD. At 17 patients from them aneurysm of the ascending aorta was diagnosed, 33 patients with the normal sizes of aorta have made the group of clinical comparison. All samples of the aortic wall were exposed to histological research. As a result of the spent analysis 2 types aortic aneurysms are revealed. The first type is aneurysm with connective tissue disorders as a result of decrease of maintenance Sr, Mn, Fe, Cr, Ni, Ca and raised maintenance of K, Rb, Se, As. It's characteristic for aortic aneurysm of the Marfan's syndrome and for 40% patients with IHD. The second type aortic aneurysms is atherosclerotic, with increase of maintenance Ca in the vessel wall from 1000 to 18000 ppm and increase maintenance of Fe, Co, Sr in comparison with the first type. That is characteristic for 60% of patients with IHD.