Ultrasonographic analysis of the dynamics of distraction tibial regenerate bone structural state in patients with achondroplasia

The aim of this study was to analyze the dynamics of the structural state of distraction tibial regenerate bone using ultrasonography in patients with achondroplasia in the process of treatment. Patients with achondroplasia at the age of 9-18 years (n=25) were examined. Leg bone lengthening was performed using the techniques of mono- and bifocal distraction osteosynthesis. Regenerate bones were evaluated by ultrasonography technique in the periods of 10, 20, 30 and 60 days after distraction onset and in the period of fixation with linear and sector sensors of 7.5 mHz using the modes of 2D and energy Doppler. Sonometric sizes, echo-density value, vascularization of distraction regenerate bone were measured. It was demonstrated that only dynamical examination allows to diagnose and predict the process of reparative osteogenesis with high accuracy.