Effect of 60-day sodium benzoate and ionizing radiation on ultrastructure of mandibular bone mineral in rat

The aim of the paper was to study the ultrastructure of the mandibular bone mineral in rats after 60 days of sodium benzoate injection and ionizing radiation, both as individual experimental factors and in combination, and also to examine the effects sea-buckthorn oil as a potential corrector. Materials and Methods. The authors examined 240 white adult male rats, which were divided into 8 groups: Group 1 - control animals; Group 2 - animals exposed to intragastric sodium benzoate (60 days); Group 3 - rats exposed to ionizing radiation (total dose 4 Gy), Group 4 - animals exposed to both experimental factors; Group 5 - rats treated with sea buckthorn oil (300 mg/day/kg); Groups 6-8 -animals who received sea buckthorn oil (300 mg/day/kg) on the background of isolated and combined experimental effects. The ultrastructure of the mandibular bone mineral was studied by X-ray diffraction method. Results. In Group 2, the authors revealed an increase in the size of the unit cells along the axes a and c by 0...