Effect of immune inflammation on the development of halvanosis symptoms in the mouth

The objective of this study was to assess the role of immune inflammation in the development of clinical symptoms of halvanosis in the mouth. When analyzing the parameters of local immunity in patients with signs of halvanosis the authors revealed an elevated content of TNF alpha cytokines, which indicates a presence of immune-mediated inflammation of oral mucosa. For the first time, the role of immune inflammation in the development of halvanosis was detrmined, and immunological merkers in the oral fluid were revealed.