Influence of dry extract Serratula centauroides L. on the functional status of central nervous system

The eхperiments were conducted on white rats (Wistar). We studied the effect of dry extract Serratula centauroides L. roots on the behavior of animals in tests "open-field" and CRPA. It has been established that the extract at the doses of 50 and 100 mg / kg increases orienting-exploratory behavior of animals in the test "open-field", increasing the number of vertical posts and the number of entries into the central zone of the installation, as well as reducing the Num-lo boluses and acts of grooming. S The extract from Serratula centauroides stimulates the cognitive functions in intact animals that leads to the development of conditioned reflexes of passive avoiding in animals and causes the safety of a memorable trace in the remote period after training in the passive avoidance reaction (PAR) test. The plant extract has the essential nootropic effect at the dose of 100 mg/kg.