Influence of control glycemia on parameters of heart rhythm variability, QT and JT-intervals in patients with ischemic heart disease and type 2 diabetes

The aim. The study was parameters of heart rhythm variability, QT- and JT-intervals in patients with ischemic heart disease and type 2 diabetes (DM). Material and methods. 131 patients aged 3069 years with unstable angina and acute myocardial infarction has been included in research. Among observable in 101 (71.6 %) patients the DM is diagnosed. Results. It is revealed, that absence of the adequate control of glycemia in patients with DM (level of glycosylated hemoglobin more than 6.5%) resulted in decrease as parasympathetic and sympathetic influences of vegetative nervous system on the sinus node. Development of repeated coronary events in patients with DM within one year of supervision associated with reduction of mainly sympathetic influences by heart (decrease of the parameter LF and relation of spectra LF/HF) that was accompanied by infringement depolarization and repolarization of myocardium. The greatest reduction of parameter LF came to light in patients with fatal outcome within one year of supervision. Conclusion. Absence of the adequate control glycemia is accompanied by infringement of regulation of vegetative nervous system in patients with ischemic heart disease and type 2 diabetes.