Effect of L-arginine on the dynamics of cardio-specific enzymes in the blood in rabbit with simulated atherosclerosis during short-term adaptation to high altitudes

In order to clarify the effect of L-arginine on the course of experimental atherosclerosis in rabbits, we examined the following indicators of cardiac-specific enzymes: high-sensitivity C-reactive protein and troponin I in blood serum. The biological effect of L-arginine, which plays an important role in regulating the functional state of the vascular wall in atherosclerotic lesions, is discussed. It was found that oral administration of L-arginine at a dose of 170 mg/kg body weight once a day for 30 days to animals with experimental atherosclerosis leads to a decrease in the concentration of the studied parameters of cardiac-specific enzymes in the blood.